An unbiased method for evaluating the genome-wide specificity of base editors in rice

Shuai Jin, Qiang Gao, Caixia Gao

Published: 2020-12-20 DOI: 10.1038/s41596-020-00423-y

base editors

genome-wide specificity

rice

whole-genome sequencing

off-target analysis

AI 解读

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Base editors can achieve targeted genomic base conversion. However, the off-target issue is one of the major concerns in their application. Whole-genome sequencing (WGS) at the individual level can provide direct information on genome-wide specificity, bu
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ACKNOWLEDGMENTS

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An unbiased method for evaluating the genome-wide specificity of base editors in rice

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