Snapshot photoacoustic topography through an ergodic relay of optical absorption in vivo

Lei Li, Yang Li, Yide Zhang, Lihong V. Wang

Published: 2021-04-11 DOI: 10.1038/s41596-020-00487-w

Photoacoustic topography

Ergodic relay

In vivo imaging

Wide-field imaging

PULSE WAVE PROPAGATION

AI 解读

Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail

Profiling native pulmonary basement membrane stiffness using atomic force microscopy

Genetic circuit design automation with Cello 2.0

Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages

Scalable dual-omics profiling with single-nucleus chromatin accessibility and mRNA expression sequencing 2 (SNARE-seq2)

A practical guide to scanning light-field microscopy with digital adaptive optics

Effective high-throughput isolation of fully human antibodies targeting infectious pathogens

Improved sampling and DNA extraction procedures for microbiome analysis in food-processing environments

MOF-derived nanoporous carbons with diverse tunable nanoarchitectures

Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease

查看全部

Sections

Figures

References

Photoacoustic tomography (PAT) has demonstrated versatile biomedical applications, ranging from tracking single cells to monitoring whole-body dynamics of small animals and diagnosing human breast cancer. Currently, PAT has two major implementations: phot
Introduction
Materials
Procedure
Troubleshooting
Timing
Anticipated results
References
ACKNOWLEDGMENTS

Weber, J., Beard, P. C. & Bohndiek, S. E. Contrast agents for molecular photoacoustic imaging. Nat. Methods 13, 639–650 (2016).
Ntziachristos, V. Going deeper than microscopy: the optical imaging frontier in biology. Nat. Methods 7, 603–614 (2010).
Wang, L. H. V. & Hu, S. Photoacoustic tomography: in vivo imaging from organelles to organs. Science 335, 1458–1462 (2012).
Zhang, H. F., Maslov, K. & Wang, L. V. In vivo imaging of subcutaneous structures using functional photoacoustic microscopy. Nat. Protoc. 2, 797–804 (2007).
Beard, P. C. Biomedical photoacoustic imaging. Interface Focus 1, 602–631 (2011).
Xu, M. & Wang, L. V. Universal back-projection algorithm for photoacoustic computed tomography. Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 71, 016706 (2005).
Matthews, T. P., Poudel, J., Li, L., Wang, L. V. & Anastasio, M. A. Parameterized joint reconstruction of the initial pressure and sound speed distributions for photoacoustic computed tomography. SIAM J. Imaging Sci. 11, 1560–1588 (2018).
Li, L. et al. Single-impulse panoramic photoacoustic computed tomography of small-animal whole-body dynamics at high spatiotemporal resolution. Nat. Biomed. Eng. 1, 0071 (2017).
Wang, L. V. & Yao, J. A practical guide to photoacoustic tomography in the life sciences. Nat. Methods 13, 627–638 (2016).
Li, Y. et al. Snapshot photoacoustic topography through an ergodic relay for high-throughput imaging of optical absorption. Nat. Photonics 14, 164–170 (2020).
Li, L. et al. Small near-infrared photochromic protein for photoacoustic multi-contrast imaging and detection of protein interactions in vivo. Nat. Commun. 9, 2734 (2018).
Zhang, P. et al. High-resolution deep functional imaging of the whole mouse brain by photoacoustic computed tomography in vivo. J. Biophotonics 11, e201700024 (2018).
Zhang, P., Li, L., Lin, L., Shi, J. & Wang, L. V. In vivo superresolution photoacoustic computed tomography by localization of single dyed droplets. Light Sci. Appl. 8, 36 (2019).
Jathoul, A. P. et al. Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter. Nat. Photonics 9, 239–246 (2015).
Yao, J. et al. Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe. Nat. Methods 13, 67–73 (2016).
Wu, Z. et al. A microrobotic system guided by photoacoustic computed tomography for targeted navigation in intestines in vivo. Sci. Robot. 4, eaax0613 (2019).
Li, L. et al. Label-free photoacoustic tomography of whole mouse brain structures ex vivo. Neurophotonics 3, 035001 (2016).
Yeh, C. et al. Dry coupling for whole-body small-animal photoacoustic computed tomography. J. Biomed. Opt. 22, 41017 (2017).
Razansky, D. et al. Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo. Nat. Photonics 3, 412–417 (2009).
Imai, T. et al. High-throughput ultraviolet photoacoustic microscopy with multifocal excitation. J. Biomed. Opt. 23, 1–6 (2018).
Qu, Y. et al. Dichroism-sensitive photoacoustic computed tomography. Optica 5, 495–501 (2018).
Razansky, D., Buehler, A. & Ntziachristos, V. Volumetric real-time multispectral optoacoustic tomography of biomarkers. Nat. Protoc. 6, 1121–1129 (2011).
Li, L., Zhu, L., Shen, Y. & Wang, L. V. Multiview Hilbert transformation in full-ring transducer array-based photoacoustic computed tomography. J. Biomed. Opt. 22, 76017 (2017).
Laufer, J. et al. In vivo preclinical photoacoustic imaging of tumor vasculature development and therapy. J. Biomed. Opt. 17, 056016 (2012).
Ellwood, R., Ogunlade, O., Zhang, E., Beard, P. & Cox, B. Photoacoustic tomography using orthogonal Fabry–Pérot sensors. J. Biomed. Opt. 22, 41009 (2016).
Li, L. et al. Fully motorized optical-resolution photoacoustic microscopy. Opt. Lett. 39, 2117–2120 (2014).
Yao, J. et al. High-speed label-free functional photoacoustic microscopy of mouse brain in action. Nat. Methods 12, 407–410 (2015).
Hsu, H.-C. et al. Dual-axis illumination for virtually augmenting the detection view of optical-resolution photoacoustic microscopy. J. Biomed. Opt. 23, 1–7 (2018).
Draeger, C. & Fink, M. One-channel time reversal of elastic waves in a chaotic 2D-silicon cavity. Phys. Rev. Lett. 79, 407 (1997).
Ing, R. K., Quieffin, N., Catheline, S. & Fink, M. In solid localization of finger impacts using acoustic time-reversal process. Appl. Phys. Lett. 87, 204104 (2005).
Li, Y., Wong, T. T., Shi, J., Hsu, H.-C. & Wang, L. V. Multifocal photoacoustic microscopy using a single-element ultrasonic transducer through an ergodic relay. Light Sci. Appl. 9, 1–7 (2020).
Li, Y. et al. Photoacoustic topography through an ergodic relay for functional imaging and biometric application in vivo. J. Biomed. Opt. 25, 1–8 (2020).
Fink, M. & de Rosny, J. Time-reversed acoustics in random media and in chaotic cavities. Nonlinearity 15, R1 (2001).
Eder, F. X. Moderne Messmethoden der Physik. Bd 1. 2., erweiterte Aufl. Edn (Deutscher Verlag der Wissenschaften, 1960).
Bioucas-Dias, J. M. & Figueiredo, M. A. T. A new TwIST: two-step iterative shrinkage/thresholding algorithms for image restoration. IEEE Trans. Image Process. 16, 2992–3004 (2007).

Snapshot photoacoustic topography through an ergodic relay of optical absorption in vivo

Supplementary information

Reporting Summary

Supplementary Software 1

Supplementary Data 1

推荐阅读