Measuring the elastic modulus of soft culture surfaces and three-dimensional hydrogels using atomic force microscopy

Michael D. A. Norman, Silvia A. Ferreira, Geraldine M. Jowett, Laurent Bozec, Eileen Gentleman

Published: 2021-04-13 DOI: 10.1038/s41596-021-00495-4

Atomic force microscopy

Elastic modulus

Hydrogels

Cell culture substrates

Mechanical properties

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Growing interest in exploring mechanically mediated biological phenomena has resulted in cell culture substrates and 3D matrices with variable stiffnesses becoming standard tools in biology labs. However, correlating stiffness with biological outcomes and
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ACKNOWLEDGMENTS

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Measuring the elastic modulus of soft culture surfaces and three-dimensional hydrogels using atomic force microscopy

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