BAR-Seq clonal tracking of gene-edited cells

Samuele Ferrari, Stefano Beretta, Aurelien Jacob, Davide Cittaro, Luisa Albano, Ivan Merelli, Luigi Naldini, Pietro Genovese

Published: 2021-05-23 DOI: 10.1038/s41596-021-00529-x

Gene editing

BAR-Seq

Clonal tracking

Hematopoietic stem cells

Bioinformatics

AI 解读

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Gene editing by engineered nucleases has revolutionized the field of gene therapy by enabling targeted and precise modification of the genome. However, the limited availability of methods for clonal tracking of edited cells has resulted in a paucity of in
Introduction
Materials
Procedure
Troubleshooting
Timing
Anticipated results
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References
ACKNOWLEDGMENTS

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BAR-Seq clonal tracking of gene-edited cells

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